Which of the statements about "Denaturation" given below are correct?
$A$. Denaturation of proteins causes loss of secondary and tertiary structures of the protein
$B$. Denaturation leads to the conversion of double strand of $DNA$ into single strand
$C$. Denaturation affects primary structure which gets distorted

• A
  $B$ and $C$
• B
  $A$ and $C$
• C
  $A$ and $B$
• D
  $A, B$ and $C$